Pharmacology Thesis/Dissertation Topics for MD/DNB.​

Updated for the 2026–27 MD Pharmacology and DNB batch. Click "Protocol →" next to any topic to generate a ready protocol for your thesis submission.

1. The effect of lamotrigine on working memory in rats.
2. Effectiveness of drug information pamphlets in improving patient medication adherence and usage of commonly prescribed medications and antibiotics among patients in a tertiary care hospital.
3. Study of prescription pattern of antihypertensive drugs in a tertiary care hospital.
4. A study to evaluate the antibacterial drugs used in upper-respiratory tract infection in pediatric age group.
5. 5-Fluorouracil degradation rate (5-FUDR) as a predictive biomarker for adverse effects with 5-fluorouracil/capecitabine therapy in cancer patients: a prospective phenotype-genotype association study.
6. Hepatoprotective effect of 7-methoxycoumarin in paracetamol and ethanol toxicity induced cell lines.
7. Pattern of adverse drug reaction and medication use in neonatal care units in a tertiary care hospital: a longitudinal observational study.
8. Antidiabetic and pleiotropic effects of Psidium guajava Linn. leaf extract as an add-on treatment in patients with type 2 diabetes mellitus: a randomized double-blind placebo-controlled trial.
9. Characterization of pncA mutation and treatment outcome among tuberculosis patients.
10. Characterization of cyclosporine trough (C0) and two-hour post dose concentration (C2) monitoring in children with idiopathic nephrotic syndrome.
11. Clinical characteristics and early outcome of bedaquiline containing regimens for the treatment of MDR tuberculosis.
12. Clinical characteristics and treatment outcome of isoniazid mono-resistant tuberculosis patients: a mixed-method study.
13. Evaluation of the prescription pattern of drugs in different OPDs of a tertiary care hospital.
14. The cytokine levels and miRNA expression in patients with major depressive disorder and its modulation by silymarin.
15. Subclinical hypothyroidism and plasma levels of commonly prescribed antiepileptic drugs: a cross-sectional study.
16. Pharmacogenetics of sodium valproate-induced weight gain.
17. Formulation and evaluation of topical preparation of Lawsonia inermis L. (Lythraceae) for the evaluation of capecitabine-induced hand-foot syndrome in cancer patients.
18. Are the users of angiotensin converting enzyme inhibitors (ACE-I) and angiotensin receptor blockers (ARBs) at a higher risk of severe COVID-19? A case-control study.
19. Association of nucleoside diphosphate-linked moiety X-type motif 15 (NUDT15) C415T and inosine triphosphate pyrophosphatase (ITPA) C94A genetic polymorphisms with azathioprine induced adverse effects.
20. Effect of VDR (vitamin D receptor) gene polymorphisms on efficacy of zoledronic acid in women with postmenopausal osteoporosis: a cross-sectional study.
21. Cytogenetic and molecular characterization of teenage and young adult acute lymphoblastic leukaemia with special emphasis on identification of Philadelphia like profile.
22. Influence of EPHX1 c.337T>C and UGT2B7*2 genetic polymorphism on carbamazepine maintenance dose requirement in persons with epilepsy.
23. Estimating incremental cost of treating antimicrobial-resistant infections.
24. Study of prescription pattern of anti-epileptic agents in a tertiary care hospital.
25. Evaluation of anti-inflammatory and analgesic activities of thiophene derivatives in Wistar albino rats.
26. Evaluation of learning and memory enhancing activities of thiazolidinone arecoline derivatives in Wistar albino rats.
27. Evaluation of hepatoprotective effect of gallic acid in murine model of isoniazid-induced hepatotoxicity.
28. Study of prescription pattern of antimicrobial drugs in a tertiary care hospital.
29. Evaluation of effect of ciprofloxacin and levofloxacin on depressive behaviour in mice.
30. Evaluation of anti-ulcer activity of vanillin using stress and aspirin induced ulcer models in Wistar albino rats.
31. A comparative study of efficacy and safety of timolol versus latanoprost in the treatment of primary open angle glaucoma at a tertiary care hospital.
32. A comparative prospective study to assess the efficacy and safety of iron sucrose versus iron sorbitol citric acid complex in pregnant women with iron deficiency anaemia in a tertiary care hospital.
33. Comparison of the effects of imipramine and fluoxetine on the diagnostic parameters of metabolic syndrome in patients with depressive episode at a tertiary care hospital.
34. A comparative study of efficacy and safety of intralesional triamcinolone with verapamil in the treatment of keloid and hypertrophic scar in a tertiary care hospital.
35. A comparative study of the clinical efficacy and safety of topical retapamulin and mupirocin in the treatment of acute bacterial skin infections.
36. A prospective randomized open-labelled comparative study of the clinical efficacy and safety of the fixed dose combination of arterolane maleate and piperaquine phosphate with artesunate and sulfadoxine-pyrimethamine in uncomplicated falciparum malaria.
37. Prospective comparative study of effect of two cephalosporin sulbactam combinations in chemoprophylaxis of open reduction and internal fixation surgery in closed limb fractures.
38. The efficacy and adverse drug profile of risperidone versus olanzapine in the treatment of patients with bipolar affective disorder on combination therapy: a prospective, naturalistic, hospital-based clinical study.
39. Comparison of the effect of selective serotonin reuptake inhibitors and selective serotonin norepinephrine reuptake inhibitors on body mass index in patients on long term treatment.
40. Comparative assessment of the efficacy of morning dose versus evening dose levothyroxine in hypothyroid patients.
41. Study of prescription pattern of antitubercular drugs in a tertiary care hospital.
42. Comparative assessment of oral and local probiotics as an adjunct to standard therapy for vulvovaginitis.
43. Antiasthmatic effect of ethanolic extract of Moringa oleifera (drumstick) seed kernels in an experimental animal model.
44. Comparison of efficacy and safety of newer antifungal agent sertaconazole with clotrimazole and fluconazole in the treatment of acute vulvovaginal candidiasis.
45. Preliminary evaluation of anticonvulsant activity of aqueous extract of Adhatoda vasica leaves in male and female albino rats.
46. Preliminary evaluation of hypoglycemic activity of methanol extract of roots of Acorus calamus in alloxan induced diabetic albino rats.
47. To study effectiveness and tolerability of opipramol in the treatment of generalized anxiety disorder and somatoform disorders.
48. A comparative study for efficacy of combination therapy of inhaled levosalbutamol and ipratropium bromide against combination therapy of inhaled levosalbutamol and beclomethasone dipropionate in the treatment of bronchial asthma in adults.
49. Monitoring and evaluation of adverse drug reactions in antiretroviral therapy centre and dermatology department in a tertiary hospital.
50. A prospective observational study on pattern of steroid utilization in a rural teaching hospital.
51. A study of prescription pattern in musculoskeletal disorders causing low back pain (LBP).
52. A study of prescription pattern in the drug therapy of rheumatoid arthritis.
53. A prospective study on the use of anaesthetic agents in modern surgical practice.
54. Adverse drug reaction monitoring in a teaching hospital.
55. Study of analgesics usage in third trimester of pregnancy and its ill-effects on pregnancy course and outcome.
56. To evaluate the analgesic activity of garlic extract in rats.
57. A study to assess adverse drug reactions to antiretroviral therapy: type and risk factors in an ART centre.
58. A randomized, prospective study of single dose epidural 0.2% levobupivacaine with 25 µg fentanyl and single dose epidural 0.2% ropivacaine with 25 µg fentanyl for postoperative analgesia in patients undergoing elective lower limb surgeries.
59. A prospective study of oral betahistine and ondansetron in the prevention of postoperative nausea and vomiting, in patients undergoing tympanomastoid surgeries under local anaesthesia.
60. Effect of minoxidil on blood glucose levels in normal and type 2 diabetic model of rats and its pharmacodynamic interaction with glibenclamide: an experimental study.
61. Prescription audit of antibacterials in suspected neonatal sepsis at a tertiary care hospital.
62. Efficacy of supplementation of probiotics along with antimicrobial agents in vulvovaginal infections in a tertiary care hospital.
63. Study of anticonvulsant effect of nebivolol in maximal electroshock (MES) and pentylenetetrazole (PTZ) induced seizure models in mice.
64. A prospective study to evaluate the effect of cilostazol on the lipid profile in patients of peripheral arterial disease as an adjunct to statins.
65. Experimental evaluation of anticonvulsant activity of atorvastatin in Wistar rats.
66. A randomised controlled study to compare the efficacy of racecadotril versus diphenoxylate in acute radiation enteritis.
67. Assessment of adverse drug reactions in geriatric patients in a tertiary care hospital.
68. Factors affecting adherence to drugs and its influence on outcomes in select chronic diseases (cardiovascular disease and diabetes mellitus) at a tertiary care hospital.
69. Patterns and determinants of polypharmacy in perioperative patients in general surgical wards of a tertiary care hospital: a prospective observational study.
70. Pattern of use of analgesics for postoperative pain management in adults undergoing laparotomy surgery: a prospective observational study in a tertiary care hospital.
71. Patterns of drug use and factors affecting adherence to medication in rheumatoid arthritis: a prospective, observational, hospital-based study.
72. Study of prescription pattern in the management of herpes zoster.
73. A comparative study of efficacy and safety of alternate day rosuvastatin dosing versus daily rosuvastatin dosing in patients with dyslipidemia.
74. Evaluation of the appropriateness of prescribing in geriatric patients admitted in various departments of a teaching hospital.
75. A prospective study of various poisoning, pattern, pharmacological management and their outcome in a tertiary care hospital.
76. Drug utilization study of antibiotics use in orthopaedic units of a tertiary care hospital.
77. A comparative study to evaluate the efficacy, tolerability and response rates of two antidepressants escitalopram with sertraline in patients of major depressive disorder.
78. Role of antimicrobial agents for the prevention of surgical site infections with pharmacoeconomics in the general surgery units.
79. A prospective study to compare efficacy and tolerability of ranolazine and nicorandil in patients with angina pectoris.
80. Drug utilisation study of anticonvulsant agents in paediatric unit in a tertiary care hospital.
81. Comparative study of safety and efficacy of inhalation anti-asthma drugs versus systemic anti-asthma drugs in a tertiary care hospital.
82. Study of prescription pattern of antiemetic drugs in a tertiary care hospital.
83. A comparative study of antinociceptive activity of paroxetine with pethidine in acute pain in albino rats.
84. A comparative study of efficacy, tolerability and safety profile of fluoxetine with desvenlafaxine in patients with depression in a tertiary care hospital.
85. A comparative study of efficacy of silodosin and tamsulosin in patients of lower ureteric calculi in a tertiary care hospital.
86. A prospective comparative efficacy and safety study of topical retapamulin and mupirocin.
87. A comparative study of the efficacy and safety of levocetirizine and rupatadine.
88. A comparative study of the efficacy and safety of amitriptyline and topiramate in the prophylaxis of migraine.
89. A comparative study of intravenous paracetamol and tramadol for postoperative analgesic efficacy in orthopedic surgeries at a tertiary care hospital.
90. Study of anti-inflammatory activity of Ficus racemosa Linn. stem bark extract in albino rats.
91. Study of analgesic activity of Murraya koenigii leaves extract in albino mice.
92. A comparative study of the efficacy and safety of oral flunarizine to oral propranolol in prophylaxis of migraine.
93. A comparative study of efficacy and tolerability of oral desloratadine, ketotifen and rupatadine in seasonal allergic rhinitis.
94. A study of the pattern of drug use for postoperative analgesia following lower abdominal surgeries in a tertiary care hospital.
95. Study of prescription pattern of oral contraceptive pills in a tertiary care hospital.
96. A study of the pattern of preanaesthetic medication for major surgeries under general anaesthesia in a tertiary care hospital.
97. A comparative study of efficacy and tolerability of olopatadine, ketotifen and epinastine in seasonal allergic conjunctivitis.
98. A comparative study of efficacy and tolerability of methotrexate, sulfasalazine and leflunomide in rheumatoid arthritis.
99. A study of the pattern of drug use for general and regional anesthesia for caesarean section and to compare the maternal and neonatal outcome.
100. Evaluation of nephroprotective action of ethanolic extract of leaves of Alocasia macrorrhizos in rats.
101. Study of prescription patterns and pharmacoeconomic evaluation of anti-epileptic drugs.
102. A prospective study on pattern of poisoning among adult inpatients in a tertiary care hospital.
103. Evaluation of glycemic index and insulin index of a marketed sugar product.