Biochemistry Thesis/Dissertation Topics for MD/DNB

Updated for the 2026–27 MD Biochemistry and DNB batch. Click “Protocol →” next to any topic to generate a ready protocol for your thesis submission.

A comparison of the Prevalence of Syndrome X in Middle Aged Males Using International Diabetes Federation (IDF) Versus the World Health Organisation (WHO) criteria and correlation with the prevalence of Insulin Resistance and Microalbuminuria.
Role of Antioxidants Vitamin E and Vitamin C on protein Oxidation in Leprosy.
Study of Lipid Peroxidation and Antioxidant Mechanism in patients of Acute Cerebrovascular Stroke.
Study of Homeostatic Model assessment of Insulin Resistance (HOMA-IR) Index and relationship of Serum Insulin levels with Serum TG & Serum HDL in Obesity.
Evaluation of Thyroid Function Test in Acute Coronary Syndrome.
Study of small dense low density lipoprotein cholesterol, lipid profile and paraoxonase-1 in postmenopausal women.
Microalbumin, Paraoxonase 1 and hsCRP in Diabetes Mellitus.
Study of Serum Magnesium, Serum Calcium, Serum Iron and Total Iron Binding Capacity levels in Hypertensive Pregnant women.
Alterations in Serum Electrolytes and Blood Gas Parameters in Burn Patients.
Study of Nitric Oxide synthesis, its effect on CSF Protein and Lipids and its correlation with CSF antibody levels in Meningitis.
Evaluation of Extent of Protein Oxidation in Cataract Lenses.
Study of Nitric Oxide synthesis and its effects on Lipids and Proteins in Lymphatic Filariasis.
Study of antioxidant status in amniotic fluid in pregnancy induced hypertension.
Study of Thyroid Function in Depression.
Lipid profile in Chronic Kidney Disease with Nephrotic Syndrome and without Nephrotic Syndrome.
Isolation and Evaluation of diagnostic potential of tubercular ESAT-6 antigen and its antibody.
Study of cardio-metabolic abnormalities among adolescents attending a primary health centre.
Study of Serum Lipid Profile, Proteins, Ferritin, Calcium, ALP levels in Breast Carcinoma patients.
Trace elements (magnesium, zinc, copper) in chronic alcoholic liver disease.
A study of creatine kinase activity, serum creatinine and creatinine clearance in hypothyroidism.
A study of serum levels of vitamin D in impaired glucose tolerance and type 2 diabetes mellitus.
A study of renal profile in obese hypertensive patients in comparison to non-obese hypertensive patients.
Development of reference ranges for blood glucose and lipid profile in a healthy adult population.
Assessment of glomerular filtration rate and renal function tests in chronic alcoholics.
Serum protein pattern, C-reactive protein and ceruloplasmin levels in alcohol-dependent males.
Evaluation of bone alkaline phosphatase and urinary calcium/creatinine ratio in elderly age group.
Ascitic fluid biomarkers for the early diagnosis of spontaneous bacterial peritonitis.
A study of thyroid dysfunction and lipid profile in type 2 diabetes mellitus.
Effect of yoga on oxidant and antioxidant status in type 2 diabetes mellitus.
Study of insulin resistance and serum lipid profile in gestational hypertension and preeclampsia.
Evaluation of serum superoxide dismutase, paraoxonase, malondialdehyde and high-sensitivity C-reactive protein in ischemic stroke patients with and without type II diabetes mellitus.
Lipid profile, apo-A and apo-B levels in subclinical hypothyroidism.
Study of serum homocysteine, C-reactive protein and uric acid in preeclampsia.
Peroxidative stress and antioxidant status in urolithiasis.
Relationship between insulin resistance and hypothyroidism.
Study of serum lipoprotein (a) and lipid profile in polycystic ovarian syndrome.
Study of serum malondialdehyde and ascorbic acid levels in pre-eclampsia.
A comparative study of serum uric acid, C-reactive protein and serum calcium in preeclampsia and normal pregnancy.
Lipid peroxidation, dyslipidemia and glycated haemoglobin in controlled and uncontrolled type 2 diabetes mellitus.
Oxidative stress, estrogen levels and antioxidant defense in patients with polycystic ovarian syndrome.
Study and evaluation of serum levels of complement-3 and sialic acid in patients of coronary artery disease.
Evaluation of biochemical markers of oxidative and nitrosative stress pathways in major depression.
Biochemical significance of ischemia modified albumin in comparison with other routine markers of cell necrosis in acute coronary syndrome.
Study of levels of nitric oxide and lipid peroxides in preeclampsia.
Sialic acid levels in type 2 diabetes mellitus (without complications) and diabetic nephropathy - a case control study.
Thyroid function in type 2 diabetes mellitus (without complications) and diabetic nephropathy - a case control study.
Study of serum adiponectin and leptin levels in patients with type 2 diabetes mellitus.
Study of serum cystatin for early detection of renal dysfunction and thereby early detection of hepatorenal syndrome in alcoholic cirrhosis patients.
Study of serum homocysteine, folic acid and vitamin B12 levels in patients of vascular dementia.
Role of intact parathormone (iPTH) and other biochemical parameters in early diagnosis of mineral disturbances in patients with chronic kidney disease.
Study of serum lipoprotein(a), apolipoprotein B, hs-CRP and lipid profile in ischemic heart disease.
Effect of hemodialysis in patients with chronic renal failure on lipid profile, serum paraoxonase-1 activity and malondialdehyde levels.
Study of serum high-sensitivity C-reactive protein, ferritin, insulin, C-peptide and glycated hemoglobin in patients with type 2 diabetes mellitus.
Study of paraoxonase, myeloperoxidase activities and malondialdehyde levels in preeclampsia.
Study of serum ferritin and glycated hemoglobin in type 2 diabetes mellitus.
The study of serum ferritin and serum myeloperoxidase levels in type 2 diabetic males on oral hypoglycemic agents.
Serum complement C3 levels in women with polycystic ovarian syndrome.
A comparative study of hs-CRP, serum magnesium and serum zinc in type 2 diabetes mellitus patients and non-diabetics.
Study of serum ADA (adenosine deaminase) activity & its correlation to HbA1c in type 2 diabetes mellitus.
A study on serum leptin levels and lipid profile in patients with skin tag.
A study on serum cystatin C levels in type 2 diabetes mellitus.
Prognostic significance of ischemia modified albumin and high-sensitivity C-reactive protein in patients with acute ischemic stroke.
Significance of anti thyroperoxidase & anti thyroglobulin antibody titres in patients with subclinical hypothyroidism.
Significance of biochemical markers of foetal nutrition in the cord blood in correlation with maternal placental alkaline phosphatase levels.
Study of sex hormone binding globulin and high-sensitivity C-reactive protein in preeclampsia.
Utility of prostate-specific antigen and its correlation with cancer antigen 15-3 and carcinoembryonic antigen in female breast carcinoma.
A case control study of serum γ-glutamyltransferase, high-sensitivity C-reactive protein and insulin levels in patients with metabolic syndrome.
Correlation of oxidative stress and antioxidant defense in iron deficiency anaemia of pregnancy.
Carbamylated hemoglobin as a marker for predicting progression of renal failure. A comparison among diabetic and non-diabetic chronic kidney disease.
Evaluation of serum vitamin B12, folic acid and homocysteine levels in stroke patients.
Study of serum ferritin, HbA1c, nitric oxide, uric acid levels in type 2 diabetes mellitus.
Cystatin C as an early biomarker of renal impairment in patients with type 2 diabetes.
Study of serum protein thiols, uric acid, C-reactive protein in chronic renal failure.
Study of serum iron status and serum peroxidase activity of ceruloplasmin in preeclampsia.
Glycated hemoglobin and fructosamine levels in chronic alcoholic liver disease.
Study of serum levels of lipid profile, malondialdehyde, superoxide dismutase and paraoxonase in preeclampsia and normal pregnancy.
Significance of serum adenosine deaminase and 5′-nucleotidase in acute hepatitis.
Oxidative stress induced senescence of RBC membrane in type 2 diabetes mellitus patients.
Study of serum lipoprotein(a), acute phase protein, serum electrolytes levels and their clinical implications in pre-eclampsia.
Evaluation of lipid profile changes before, during, & after low dose continuous/intermittent isotretinoin therapy for acne vulgaris.
A correlative study of copper, ceruloplasmin, iron, total iron binding capacity and total antioxidant capacity in diabetic nephropathy.
A correlative study of copper, ceruloplasmin, total antioxidant capacity, iron and total iron binding capacity in alcoholic liver disease and healthy controls.
Role of lecithin cholesterol acyl transferase and apolipoprotein A-I in diabetes mellitus.
Role of cardiac troponin I and creatine kinase-MB as a biochemical marker of myocardial damage in newborns with perinatal asphyxia.
Study of hepatic biochemical alterations induced by Plasmodium falciparum and Plasmodium vivax - a comparative study.
Study of serum copper, magnesium and glycated hemoglobin levels in patients with type 2 diabetes mellitus.
A comparative study of serum amylase, estimated glomerular filtration rate and serum insulin levels in metabolic syndrome and diabetes mellitus (type 1 and type 2).
A study of serum ischemia modified albumin, serum fibrinogen and hs-CRP in type 2 diabetes mellitus (without hypertension) and diabetes with hypertension - a case control study.
Evaluation of oxidative stress, serum paraoxonase level and dyslipidemia in psoriasis.
Lipid profile and fibrinogen levels in smokers and non-smokers.
A comparative study of serum magnesium, copper and serum total cholesterol in type 2 diabetes mellitus with and without retinopathy and healthy controls.
A correlative study of ischemia modified albumin, malondialdehyde and high-sensitivity C-reactive protein in pre-eclampsia, normal pregnancy and controls.
Study of thyroid profile and high-sensitivity C-reactive protein in persons with psoriasis.
A cross-sectional study to correlate biochemical parameters with risk factors of coronary heart disease.
A study on assessing the significance of serum leptin and insulin levels in polycystic ovarian syndrome patients.
A study on serum leptin levels and lipid profile in hypertensive obese cases.
Study of serum adenosine deaminase, oxidative stress and glycated hemoglobin in type 2 diabetes mellitus - a case control study.
A study of serum magnesium and dyslipidemia in type 2 diabetes mellitus patients.
Comparative study of oxidative stress, antioxidants, HDL and apo A-I in whisky and rum consumers.
Evaluation of serum adenosine deaminase activity in relation to components of metabolic syndrome.
Metabolic syndrome in patients with abdominal obesity.
Correlation between oxidative stress, lipid profile and inflammatory marker (hs-CRP) in coronary artery disease.
A case control study on correlation of serum prealbumin, albumin, high-sensitivity C-reactive protein with other biochemical parameters of malnutrition in haemodialysis patients.
A comparative study of serum markers cystatin C and paraoxonase levels in pre-eclamptic primigravidae at a tertiary care hospital.
Serum cathepsin K: its correlation with radiological destruction of joints in established rheumatoid arthritis.
Study of serum lipid profile and liver enzymes in ultrasound diagnosed cases of non-alcoholic fatty liver disease (NAFLD).
Study of G6PD, zinc and HbA1c levels in type 2 diabetes mellitus patients.
Lipid profile & urinary protein - creatinine ratio in pre-eclampsia: a short study.
Study on vitamin D status among women attending a tertiary care hospital.
Comparison of methodology effect on albumin corrected serum calcium in patients with renal and hepatic failure: a cross sectional study.
Correlation between ischemia modified albumin (IMA) and glycosylated hemoglobin (HbA1c) and development of diabetic retinopathy in patients with type 2 diabetes mellitus.
Study of serum ferritin levels as a marker in type 2 diabetes and its relationship with serum insulin.
Serum β-hCG, serum prolactin and lipid profile levels as predictors of pregnancy induced hypertension in early second trimester.
Serum osteocalcin levels in metabolic syndrome.
Serum leptin in pre-diabetes and type 2 diabetes mellitus.
Study of microalbuminuria as a nephropathic marker in type 2 diabetes mellitus and its correlation with the glycated hemoglobin.
Evaluation of different urinary constituents and their ratios in patients with urolithiasis.
To evaluate the relationship between insulin resistance and serum lipoproteins and estimation of luteinizing hormone in polycystic ovarian syndrome.
Study of serum ischemia modified albumin, CK-MB, troponin-I, AST, LDH in acute myocardial infarction within six hours of onset of chest pain.
Study of serum adenosine deaminase, C-reactive protein, uric acid and nitric oxide levels in psoriasis.
Serum myeloperoxidase, apolipoprotein B and glycated hemoglobin levels in type 2 diabetes mellitus.
Study of sialic acid and nitric oxide in type 2 diabetes mellitus with and without diabetic nephropathy.
Study of serum calcium, magnesium and copper levels in patients with essential hypertension.
Study of serum sodium, potassium, calcium, magnesium, cystatin C and β2-microglobulin in pregnancies complicated by hypertension.
Study of bone related biochemical parameters in healthy and type 2 diabetic postmenopausal women.