Pharmacology Thesis/Dissertation Topics for MD/DNB.​

1.    The effect of lamotrigine on working memory in rats.

2.    Effectiveness of drug information pamphlets in improving patient medication adherence and usage of commonly prescribed medications and antibiotics among patients in a tertiary care hospital.

3.    Study of prescription pattern of antihypertensive drugs in a tertiary care hospital.

4.    A study to evaluate the antibacterial drugs used in upper-respiratory tract infection in pediatric age group.

5.    5- Fluorouracil Degradation Rate (5-FUDR) as a predictive biomarker for adverse effects with 5- Fluorouracil / Capecitabine therapy in South Indian cancer patients – a prospective phenotype genotype association study.

6.    Hepatoprotective effect of 7 – methoxy coumarin in paracetamol and ethanol toxicity induced cell lines.

7.    Pattern of adverse drug reaction and medication use in neonatal care units in a tertiary care hospital: a longitudinal observational study.

8.    Antidiabetic and pleiotropic effects of Psidium guajava Linn leaf extract. as an add on treatment in patients with type 2 diabetes mellitus – A randomized double-blind placebo controlled trial

9.    Characterization of pncA mutation and treatment outcome among tuberculosis patients

10. Characterization of cyclosporine trough (C0) and two-hour post dose concentration (C2) monitoring in children with idiopathic nephrotic syndrome

11. Clinical characteristics and early outcome of bedaquiline containing regimens for the treatment of MDR

12. Clinical characteristics and treatment outcome of Isoniazid mono-resistance tuberculosis patients: A mixed-method study

13. ICMR Rational use of medicines “Evaluation of the prescription pattern of drugs in different OPDs of a tertiary care hospital” task force project

14. The cytokine levels and miRNA expression in patients with major depressive disorder and its modulation by silymarin.

15. Subclinical hypothyroidism and plasma levels of commonly prescribed antiepileptic drugs – a cross sectional study.

16. Pharmacogenetics of sodium valproate – induced weight gain in South Indian patients

17. Formulation and evaluation of topical preparation of Lawsonia inermis L. (Lythraceae) for the evaluation of Capecitabine induced hand – foot syndrome in cancer patients

18. Are the users of angiotensin converting enzyme inhibitors (ACE-I) and angiotensin receptor blockers (ARBs) at a higher risk of severe COVID-19? – A Case Control study

19. Association of Nucleoside Diphosphate linked moiety X Type motif 15 (NUDT15) C415T and Inosine Triphosphate Pyrophosphatase (ITPA) C94A genetic polymorphisms with azathioprine induced adverse effects in south Indian patients.

20. Effect of VDR (Vitamin D Receptor) gene polymorphisms on efficacy of zoledronic acid in south Indian women with postmenopausal osteoporosis; A cross sectional study

21. Cytogenetic and molecular characterization of teenage and young adult acute lymphoblastic leukaemia with special emphasis on identification of “Philadelphia like” profile

22. Influence of EPHX1 c.337T>C and UGT2B7*2 genetic polymorphism on carbamazepine maintenance dose requirement in person with epilepsy from South Indi

23. Estimating Incremental Cost of treating Antimicrobial Resistant infections in India.

21. Study of prescription pattern of anti-epileptic agents in a tertiary care hospital

22. Evaluation of anti-inflammatory and analgesic activities of thiophene derivatives in wistar albino rats

23. Evaluation of learning and memory enhancing activities of thiazolidinone arecoline derivatives in wistar albino rats

24. Evaluation of hepatoprotective effect of gallic acid in murine model of isoniazid-induced hepatotoxicity.

25. Study of prescription pattern of Antimicrobial drugs in a tertiary care hospital.

26. Evaluation of effect of ciprofloxacin and levofloxacin on depressive behaviour in mice

27. Evaluation of anti-ulcer activity of vanillin using stress and aspirin induced ulcer models in wistar albino rats

28. A comparative study of efficacy and safety of timolol versus latanoprost in the treatment of primary open angle glaucoma at a tertiary care hospital

29. A comparative prospective study to assess the efficacy and safety of iron sucrose versus iron sorbitol citric acid complex in pregnant women with iron deficiency anaemia in a tertiary care hospital

30. Comparison of the effects of imipramine and fluoxetine on the diagnostic parameters of metabolic syndrome in patients with depressive episode at a tertiary care hospital

31. A comparitive study of efficacy and safety of intralesional triamcinolone with verapamilin treatment of keloid and hypertrophic scar in tertiary care hospital

32. A comparative study of the clinical efficacy and safety of topical retapamulin and mupirocin in the treatment of acute bacterial skin infections

33. A prospective randomized open- labelled comparative study of the clinical efficacy and safety of the fixed dose combination of arterolane maleate and piperaquine phosphate with artesunate and sulfadoxine – pyrimethamine in uncomplicated falcip

34. Prospective comparitive study of effect of two cephalosporin sulbactam combinations in chemoprophylaxis of open reduction & internal fixation surgery in closed limb fractures

35. The efficacy and adverse drug profile of risperidone versus olanzapine in the treatment of patients with bipolar affective disorder on combination therapy – a prospective, naturalistic, hospital based clinical study.

36. Comparison of the effect of selective serotonin reuptake inhibitors and selective serotonin norepinephrine reuptake inhibitors on body mass index in patients on long term treatment

37. Comparative assessment of the efficacy of morning dose versus evening dose levothyroxine in hypothyroid patients.

38. Study of prescription pattern of antitubercular drugs in a tertiary care hospital.

39. Comparative assessment of oral and local probiotics as an adjunct to standard therapy for vulvo vaginitis

40. “antiasthmatic effect of ethanolic extract of moringa oleifera (drumstick) seed kernels in an experimental animal model”.

41. Comparison of efficacy and safety of newer antifungal agent sertaconazole with clotrimazole and fluconazole in the treatment of acute vulvovaginal candidiasis.

42. Preliminary evaluation of anticonvulsant activity of aqueous extract of adhatoda vasica leaves in male and female albino rats

43. Preliminary evaluation of hypoglycemic activity of methanol extract of roots of acorus calamus in alloxan induced diabetic albino rats

44. To study effectiveness and tolerability of opipramol in the treatment of generalized anxiety disorder and somatoform disorders

45. A comparative study for efficacy `of combination therapy of inhaled levosalbutamol and ipratropium bromide against combination therapy of inhaled levosalbutamol and beclomethasone dipropionate in the treatment of bronchial asthma in adults

46. Monitoring and evaluation of adverse drug reactions in antiretroviraltherapy centre and dermatology department in a tertiary hospital

47. A prospective observational study on pattern of steroid utilization in a rural teaching hospital

48. A study of prescription pattern in musculoskeletal disorders causing low back pain(lbp) at kvg medical college, hospital,sullia,karnataka

49. A study of prescription pattern in the drug therapy of rheumatoid arthrits at kvg medical college and hospital, sullia (d.k), karnataka.

50. A prospective study on the use of anaesthetic agents in modern surgical practice at k.v.g. medical college & hospital, sullia (d.k.), karnataka.

51. Adverse drug reaction monitoring in a teaching hospital, mandya.

52. Study of analgesics usage in third trimester of pregnancy and its illeffects on pregnancy course and outcome.

53. To evaluate the analgesic activity of garlic extract in rats

54. A study to assess adverse drug reactions to anti retro viral therapy: type and risk factors in art centre at k. R. Hospital, mysore.

55. A randomized, prospective study of single dose epidural 0.2% levobupivacaine with 25µg fentanyl and single dose epidural 0.2% ropivacaine with 25µg fentanyl for post-operative analgesia in patients undergoing elective lower limb surgeries.

56. A prospective study of oral betahistine and ondansetron in the prevention of post operative nausea and vomiting, in patients undergoing tympanomastoid surgeries under local anaesthesia

57. Effect of minoxidil on blood glucose levels in normal and type 2 diabetic model of rats and its pharmacodynamic interation with glibenclamide: an experimental study

58. Prescription audit of antibacterials in suspected neonatal sepsis at a tertiary care hospital

59. Efficacy of supplementation of probiotics along with antimicrobial agents in vulvovaginal infections in a tertiary care hospital

60. Study of anticonvulsant effect of nebivolol in maximal electro shock (mes) and pentylenetetrazole (ptz) induced seizure models in mice

61. A prospective study to evaluate the effect of cilostazol on the lipid profile in patients of peripheral arterial disease as an adjunct to statins

62. Experimental evaluation of anti convulsant activity of atorvastatin in wistar rats

63. A randomised controlled study to compare the efficacy of racecadotril versus diphenoxylate in acute radiation enteritis.

64. Assessment of adverse drug reactions in geriatric patients in a tertiary care hospital

65. Factors affecting adherence to drugs and its influence on outcomes in select chronic disese (cardiovascular disease and diabetes mellitus at a tertiary care hospital

66. Patterns and determinants of poly pharmacy in perioperative patients in general surgical war ds of a tertiary care hospital: a prospective observational study

67. Pattern of use of analgesis for post-operative pain managment in adults undergoing laparotomy surgery-a prospective observational study in a tertiary care hospital

68. Patterns of drug use and factors affecting adherence to medication in rheumatoid arthritis- a prospective, observational, hospital based study

69. Study of prescription pattern in the management of herpes zoster at brims hospital, bidar

70. “a comparative study of efficacy and safety of alternate day rosuvastatin dosing versus daily rosuvastatin dosing in patients with dyslipidemia”

71. Evaluation of the appropriateness of prescribing in geriatric patients admitted in various departments in government teaching hospital, bidar institute of medical sciences, bidar. Karnataka

72. A prospective study of various poisoning, pattern, pharmacological management and their outcome in a tertiary care hospital

73. Drug utilization study of antibiotics use in orthopaedic units of basaveshwar teaching and general hospital attached to hke society mahadevappa rampure medical college gulbarga

74. A comparative study to evaluate the efficacy, tolerability and response rates of two antidepressants escitalopram with sertraline in patients of major depressive disorder.

75. Role of antimicrobial agents for the prevention of surgical site infections with pharmacoeconomics in the general surgery units.

76. A prospective study to compare efficacy and tolerability of ranolazine and nicorandil in the patients of angina pectoris at basaveshwara teaching and general hospital, gulbarga

77. Drug utilisation study of anticonvulsant agents in paediatric unit in a teritiary care hospital

78. Comparative study of safety and efficacy of inhalation anti-asthma drugs versus systemic anti-asthma drugs in a tertiary care hospital.

79. Study of prescription pattern of antiemetic drugs in a tertiary care hospital.

80. A comparative study of antinociceptive activity of paroxitine with pethidine in acute pain in albino rats

81. A comparative study of efficacy, tolerabilty and safety profile of fluoxetine with desvenlafaxine in patients with depression in a tertiary care hospital.

82. A comparative study of efficacy of silodosin and tamsulosin in patients of lower ureteric culculi in a tertiary care hospital

83. A prospective comparative efficacy & safety study of topical retapamulin and mupirocin

84. A comparative study of the efficacy and safety of levocetirizine and rupatadine

85. A comparative study of the efficacy and safety of amitryptyline and topiramate in the prophylaxis of migraine

86. A comparative study of intravenous paracetamol and tramadol for post operative analgesic efficacy in orthopedic surgeries at a tertiary care hospital, bangalore

87. Study of anti inflammatory activity of ficus racemosa linn stem bark extract in albino rats

88. Study of analgesic activity of murraya koenigii leaves extractin albino mice

89. A comparative study of the efficacy and safety of oral flunarizine to oral propranalol in prophylaxis of migraine in rajarajeswari medical college and hospital bangalore

90. A comparitive study of efficacy and tolerability of oral desloratadine, ketotifen and rupatadine in seasonal allergic rhinitis

91. A study of the pattern of drug use for postoperative analgesia following lower abdominal surgeries in a tertiary care hospital.

92. Study of prescription pattern of oral contraceptive pills in a tertiary care hospital.

93. A study of the pattern of preanaesthetic medication for major surgeries under general anaesthesia in a tertiary care hospital

94. A comparative study of efficacy and tolerability of olopatadine, ketotifen and epinastine in seasonal allergic conjunctivitis

95. A comparative study of efficacy and tolerability of methotrexate, sulfasalazine and leflunomide in rheumatoid arthritis

96. A study of the pattern of drug use for general and regional anesthesia for caesarean section and to compare the maternal and neonatal outcome

97. Evaluation of nephroprotective action of ethanolic extract of leaves of alocasia macrorrhizos in rats

98. Study of prescription patterns and pharmacoeconomic evaluation of anti-epileptic drugs

99. A prospective study on pattern of poisoning among adult in-patients in a tertiary care hospital.

100.Evaluation of Glycemic Index and Insulin Index of a marketed sugar product.